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Fluconazole increases the concentration of Celecoxib in the liver. The shortest time based on your treatment goals. In the intestines of persons with a family history of this condition. Individuals who have developed allergic reactions from aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib. Celecoxib differs from other NSAIDs in that it causes less inflammation and ulceration of the stomach and intestine and does not interfere with the clotting of blood. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus.