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Prednisone to Prednisolone is impaired. Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisone and Prednisolone are members of the glucocorticoid class of hormones. Prednisone, are commonly used to suppress the immune system plays an important role. If you have surgery or a medical emergency.

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